Bonjour à tous , je me demandais simplement comment l'ARN polymérase s'y prenait pour avancer le long du DNA ? puisque ces enzymes ont une affinité forte pour le DNA , on aurait pu penser qu'elles resteraient statiques ?
Transcription at this stage primarily results in short RNA fragments of around 9 bp in a process known as abortive transcription. Once the RNAP starts forming longer transcripts it clears the promoter. At this point, the contacts with the -10 and -35 elements are disrupted, and the σ factor falls off RNAP. This allows the rest of the RNAP complex to move forward, as the σ factor held the RNAP complex in place.